Bioinformatics aims to develop methods and software for processing large amount of biological data, and it has become an important tool in many areas of biology. This course covers major topics of bioinformatics, which includes: Introduction to bioinformatics; Collection and storage of sequences; Sequence alignment; Sequence databases; Introduction to statistics and probability analysis; Recognition of sequence patterns; Molecular evolution and phylogenetic analysis; Genome analysis and gene prediction; RNA bioinformatics; (10) Protein structure analysis and prediction; (11) Microarray data analysis; (12) Biomolecular network. This course also provides hands-on practice on some software and databases of bioinformatics.