巴塞尔大学PhD Position in the development and evolution of artificial metalloenzymes based on earth-abundant metal cofactors申请条件要求-申请方
Organizer
University of Basel
Description
The laboratory of artificial metalloenzymes at the University of Basel (Switzerland) is a World-leading team in biomimetic catalysis. Such hybrid catalysts result from the incorporation of an earth-abundant organometallic cofactor within a protein scaffold. The resulting artificial metalloenzymes (ArMs) catalyze a variety of new-to-Nature reactions. Within the MetRaZymes project, a Marie Skłodowska-Curie Actions Doctoral Network, it is proposed to engineer and evolve ArMs to functionalize inert CH bonds via radical mechanisms. To achieve this ambitious goal, the selected candidate will collaborate with leading groups throughout Europe both from academia and industry. The MSCA MetRaZyme doctoral network aims at training the next generation of researchers in the field of biocatalysis proceeding via radical mechanisms.
The University of Basel is located in the heart of Basel, one of the Europe's most active research hubs in Life Sciences. The department of chemistry consists of fifteen research groups with over 120 graduate students and 50 postdoctoral fellows, integrated in a state-of-the art infrastructure. Multiple opportunities for collaborations exist, thanks to the propitious environment provided by Life Science industries and academic laboratories (including the Biozentrum, the D-BSSE, the FMI, the national center of competence “Molecular Systems Engineering" etc.)
The selected candidate will develop interdisciplinary skills including:
Organic synthesis, purification and characterization
Organometallic aqueous chemistry
Recombinant protein expression and purification
Directed evolution
High throughput screening
Envisaged starting date: March 1, 2023.
University of Basel PhD Position in the development and evolution of artificial metalloenzymes based on earth-abundant metal cofactors项目有没有奖学金，是不是全奖Phd招生，下面我们一起看一下【大学名称】Phd的奖学金资助情况
Honors
Marie Skłodowska-Curie fellowship requirements
At the time of recruitment at the University of Basel, candidates must not have resided or carried out their main activity (studies or work) in Switzerland for more that 12 months in the 3 years immediately prior to their recruitment. The PhD student recruited at the University of Basel will complete his PhD thesis in the framework of the MSCA Doctoral Network project MetRaZymes and be fully integrated in the project. However, since this position is financed by the Swiss government, he/she will not be considered an official MSCA PhD fellow by the EU.
Full time 3 year contract. Competitive salary and mobility allowance (SFr 56'000.-/year gross salary). Extensive training opportunities. Stimulating, highly interdisciplinary research and high quality scientific environment.
University of BaselPhd申请条件和要求都有哪些？PhD Position in the development and evolution of artificial metalloenzymes based on earth-abundant metal cofactors项目是不是全奖？有没有奖学金？下面我们一起看一下University of Basel申请Phd直招需要具备哪些条件和要求，以及托福、雅思语言成绩要到多少才能申请。
Requirements
Master's degree in chemistry or biochemistry
Multidisciplinary skills (spectroscopy, biochemistry, informatics etc.)
Good communication skills in English
Ability to work independently in a multicultural and multidisciplinary environment
Ability to prioritize work and organize it within a structured schedule
Care for the detail
Intellectual independence
How to register
Application Website
Professor
Prof. Dr. Thomas R. Ward
Thomas R. Ward was born in Fribourg on January 8th 1964 as the last of 6 children of John E. Ward and Ada Lovinger Ward. He received his diploma in Chemistry in 1987 from the University of Fribourg with organic chemistry as major and inorganic chemistry as minor subjects.
From 1988 to 1991, he was a doctoral student in the group of Prof. L. M. Venanzi at the ETH Zürich in close collaboration with Prof. D. Seebach. His PhD thesis dealt with the synthesis and coordination properties of C3-symmetric phosphine ligands and their use as acetalization catalysts. This work benefited from a fruitful collaboration with Ciba Geigy which patented these systems.
Fascinated by group theory, he joined the group of Prof. R. Hoffmann at Cornell University as a Swiss National Science postdoctoral fellow (1991-1992). This theoretical excursion lead him into the fascinating field of heterogeneous catalysis: Why is rhodium so efficient at removing NO from car exhaust?
Soon after returning to Switzerland for a second postdoc in the group of Prof. C. Floriani at the University of Lausanne, he was awarded the A. Werner Fellowship and moved to Berne to undertake his independent career in Fall 1993. He obtained his Venia Legendi in 1999 and moved to the University of Neuchâtel in Fall 2000. After seven years spent at the University of Neuchâtel, he moved to the University of Basel in March 2008. The group research is centered on the exploitation of proteins as host for organometallic moieties with applications in catalysis as well as in nanobiotechnology.
He is happily married to Anouck and both are very proud of their three superb children: Benjamin Roald (1994), Samuel (1996) and Elise (1999).
Thomas R. Ward was awarded the ETH Medaille (1991), the A. Werner Fellowship (1993) as well as the A. Werner Prize (1998) and a Swiss National Science Foundation Förderungsprofessur (2000). In 2005, he was awarded the medal of the Czech Academy of Sciences for his research on artificial metalloenzymes based on the biotin-avidin technology. In 2016, he was awarded an advanced ERC grant to realize his DrEAM: the Directed Evolution of Artificial Metalloenzymes. In 2017, he was awarded the RSC Bioinorganic Chemistry Award. In 2021, he was awarded the ACS Catalysis Lectureship as well as the International Symposium on Bioorganometallic Chemistry Award for his contributions to the development of artificial metalloenzymes.
He is the director of the NCCR Molecular Systems Engineering.
Email：thomas.ward@unibas.ch
Tel.：+41 61 207 10 04
Personal website：Click to view the person website
Lab website
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