membrane-forming block copolymers with degradable blocks and linkers : synthesis and self-assembly-申请方

membrane-forming block copolymers with degradable blocks and linkers : synthesis and self-assembly

讲座

活动时间：2026.04.28 02:00 - 2026.07.28 02:00

活动地址：华南理工大学广州国际校区 c3-c204

报名

主办方

前沿软物质学院 华南软物质科学与技术高等研究院 广东省功能与智能杂化材料与器件重点实验室 软物质功能与智能杂化材料国际联合研究中心

讲座介绍

报告摘要： thesynthesis, characterizationandself-assemblybehaviouroftwotypesofamphiphilicblock copolymer systems are presented: the first system comprises block copolymers ofhydrophilic poly(ethylene glycol), peg,and hydrophobic, crystalline poly(caprolactone), pcl.specifically, a range ofpeg-b-pcl deblock copolymers and peg-b-pcl-b-peg triblock copolymers were prepared with comparable hydrophilic(peg) mass fractions of around 30 %.self-assembly via direct hydration yielded mixed phases of micelles (spherical and/or worm-like) and vesicles, along with larger aggregates. the membranesof the vesicles based on diblock copolymers were thicker than those based on triblock copolymers forpclblocksofcomparabledegreesofpolymerization. thisbehaviourcouldbecorrelatedwiththe restraints imposed on the crystallisation ofpcl by the peg blocks. the second system comprises triblock copolymers ofpegandamorphous, hydrophobic poly(dimethyl siloxane), pdms. these peg-b-pdms-b-peg triblock copolymers were designedsothat one peg arm is connected to the pdms block via asilylether bond that ispronetohydrolysis, whereas the other peg arm is connected to pdms through a hydrolyticallystablecarbosilane bond. the initial triblock had a hydrophilic (peg) mass fraction ofapproximately31 %, whereasfull hydrolysis ofthe silyl ether leads to a peg-b-pdmsdiblock copolymer withahydrophilic mass fraction of22 % as well as free peg. thus,slow hydrolysisfollowingdirect hydration resultedin vesicles with an average diameter of55 nm and a relatively narrowsizedistribution.theformationofsuch small vesicles is difficult to achieve byother means.

演讲人

jeppe madsen
jeppe madsen 分别在丹麦哥本哈根大学获化学硕士学位、在英国谢菲尔德大学获高分子化学博士学位。他曾先后在谢菲尔德大学担任博士后研究员、在工业界担任研究员，并在丹麦技术大学任职。自 2020 年起，他担任丹麦技术大学丹麦聚合物中心的高级研究员。 jeppe madsen 博士当前的研究兴趣包括特种聚合物与通用聚合物的合成、表征及应用。具体研究方向包括：利用废弃物和可再生资源制备聚合物、提高聚合物的可降解性，以及设计用于生物技术和光学等特定领域的专用聚合物。

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