鲁汶大学PhD position in Lipid-microenvironments in articular cartilage and osteoarthritis申请条件要求-申请方
主办方
鲁汶大学
PhD直招介绍
The Tissue Homeostasis and Disease research group:
We are an international, young and dynamic team performing cutting-edge molecular biology research in cartilage and osteoarthritis, the most common chronic joint disease worldwide. We exploit primary human cells and tissues from healthy and osteoarthritic joints, a wide array of molecular biology and multi-omics technologies, animal models and genetic engineering, to gain groundbreaking insights into the mechanisms that control joint homeostasis and disease. Our work is published in high-profile high-impact journals such as Science Translational Medicine, Nature Communications, PNAS and Annals of the Rheumatic Diseases. We have strong international recognition.
Selected publications
1. Monteagudo S., Cornelis F. M. F., Aznar-Lopez C., Yibmantasiri P., Guns L-A., Carmeliet P., Cailotto F., Lories R.J. DOT1L safeguards cartilage homeostasis and protects against osteoarthritis. Nature Communications, 2017, 8, 15889.
2. Cornelis F.M.F., Monteagudo S., Guns L-A, den Hollander W., Peeters T., Storms L., Meulenbelt I., Lories R.J. ANP32A regulates ATM expression and prevents oxidative stress in cartilage, brain and bone. Science Translational Medicine, 2018, 10, eaar8426.
3. Assi R., Cherifi C., Cornelis F.M.F., Zhou Q., Storms L., Pazmino S., Coutinho de Almeida R., Meulenbelt I., Lories R.J., Monteagudo S. Inhibition of KDM7A/B histone demethylases restores H3K79 methylation and protects against osteoarthritis. Annals of the Rheumatic Disease, 2023, 82, 963.
4. Escribano-Núñez A, Cornelis FMF, De Roover A, Sermon A, Cailotto F, Lories RJ, Monteagudo S. IGF1 drives Wnt-induced joint damage and is a potential therapeutic target for osteoarthritis. Nature Communications, 2024, 15, 9170.
5. Zhou Q, Ghorasaini M, Cornelis FMF, Assi R, de Roover A, Giera M, Monteagudo S, Lories RJ. Lipidomics unravels lipid changes in osteoarthritis articular cartilage. Annals of the Rheumatic Disease, 2025, 84(7):1264-1276.
The Skeletal Biology and Engineering Research Centre at KU Leuven:
The Skeletal Biology and Engineering (SBE) Research Centre, located on the Campus Gasthuisberg of the University of Leuven, contributes to a better understanding of the biology that underlies musculoskeletal diseases with the ultimate goal to develop more effective and specific therapies. The SBE is currently composed of more than 60 scientists in 4 independent research groups. We foster close collaborations with in silico modelling and with tissue engineering experts, thereby establishing a strong multidisciplinary environment.
Project
Lipids are not only structural components of membranes or energy stores. They are also diverse signaling molecules that powerfully orchestrate cell identity. In tissues such as cartilage, lipids are not uniformely distributed but organized in micro-environments that shape cell behaviour in health and disease. We hypothesize that these lipid micro-enviroments sustain tissue homeostasis in the joint, and that their disruption leads to osteoarthritis. We are studying these lipid microenviroments using spatial transcriptomic and lipidomic approaches, and linking these observations with gain- and loss of function experiments ex vivo and in vivo. Understanding the mechanisms linked with disease-associated lipids in the joint can unveil novel therapeutic targets, ultimately alleviating OA burden and enhancing patient outcomes.
KU Leuven strives for an inclusive, respectful and socially safe environment. We embrace diversity among individuals and groups as an asset. Open dialogue and differences in perspective are essential for an ambitious research and educational environment. In our commitment to equal opportunity, we recognize the consequences of historical inequalities. We do not accept any form of discrimination based on, but not limited to, gender identity and expression, sexual orientation, age, ethnic or national background, skin colour, religious and philosophical diversity, neurodivergence, employment disability, health, or socioeconomic status. For questions about accessibility or support offered, we are happy to assist you at this email address( https://www.kuleuven.be/wieiswie/en/person/g0003537 ).
鲁汶大学 PhD position in Lipid-microenvironments in articular cartilage and osteoarthritis项目有没有奖学金，是不是全奖Phd招生，下面我们一起看一下【大学名称】Phd的奖学金资助情况
项目资助情况
Offer
A full-time PhD research contract for one year with the possibility to extend (at least) 3 more years thereafter. The position is immediately available. You are stimulated to apply for a predoctoral fellowship.
The opportunity to work on a high impact, beyond state-of-the-art project with experienced mentors in a successful team.
We support PhD students with excellent (daily) guidance and training, and provide the opportunity to participate in (inter)national collaborations and conferences
A stimulating international, multidisciplinary and dynamic research environment where quality, professionalism and collaborative team spirit are encouraged.
鲁汶大学Phd申请条件和要求都有哪些？PhD position in Lipid-microenvironments in articular cartilage and osteoarthritis项目是不是全奖？有没有奖学金？下面我们一起看一下鲁汶大学申请Phd直招需要具备哪些条件和要求，以及托福、雅思语言成绩要到多少才能申请。
申请要求
Profile
You have an excellent academic record and hold a Master's degree in any area of biology or biomedical sciences. Candidates who have not yet completed their master's thesis at the time of this application are encouraged to apply.
Previous laboratory hands-on experience with omic technologies and their analysis, cell culture and biochemical assays is desired, but not essential. Experience with laboratory animals and holding a Felasa B certificate is also a plus.
You are a proactive, ambitious, dynamic person and show spirit for initiative and problem-solving. You take great care and precision in your work, and are able to work independently but also as part of a team.
You have excellent oral and written communication skills in English.
报名方式
申请链接
招生人信息
Prof. dr. Rik Lories,Prof. dr. Silvia Monteagudo
邮箱：rik.lories@kuleuven.be
相关资源
扫描二维码
下载申请方APP
下载申请方APP
扫描二维码
下载申请方APP